Can Charcot-Marie-Tooth disease affect the heart?

Abstract. Charcot-Marie-Tooth disease (peroneal muscular atrophy) has been reported to cause cardiac arrthymias and conduction disturbances in association with peripheral muscle atrophy.

What is the life expectancy of someone with Charcot-Marie-Tooth disease?

CMT isn’t usually life-threatening and rarely affects muscles involved in vital functions like breathing. People with most forms of CMT have a normal life expectancy.

What body systems are affected by Charcot-Marie-Tooth disease?


  • Charcot-Marie-Tooth disease (CMT) is the umbrella term for a range of inherited genetic conditions affecting the peripheral nervous system (the nerves stretching from the spinal cord to the muscles).
  • Symptoms include progressive weakness and muscle wasting of the legs and arms.

Does Charcot-Marie-Tooth affect blood pressure?

Does CMT affect blood pressure? As far as we know, CMT does not directly affect blood pressure.

Is Charcot-Marie-Tooth disease life threatening?

CMT is not life threatening and most people with the condition have the same life expectancy as a person without the condition. But it can make everyday activities very difficult. Living with a long-term progressive condition can also have a significant emotional impact.

What is the difference between Charcot and Charcot-Marie-Tooth?

Charcot-Marie-Tooth is an inherited peripheral neuropathy, causing muscle weakness and sensory loss in the arms, hands, feet and legs. Charcot foot is a condition causing weakening of the bones in the foot in people who have nerve damage. Oftentimes, people with diabetes get Charcot Foot.

Is Charcot-Marie-Tooth disease fatal?

CMT is not a fatal disease. Most people with it live to a normal age and remain active. In rare cases, it may affect the muscles you need to breathe. Because this can be especially dangerous at night, you may need a nighttime breathing assistive device.

Does Charcot-Marie-Tooth affect the brain?

CMT causes damage to the peripheral nerves, which carry signals from the brain and spinal cord to the muscles and relay sensations, such as pain and touch, to the brain and spinal cord from the rest of the body.

Is Charcot-Marie-Tooth a disability?

Medically Qualifying Under A Disability Listing: CMT is a form of peripheral neuropathy, meaning it affects the nerves and muscles in the arms, legs, hands, and feet. The Social Security Administration (SSA) has a standard disability listing for this type of neurological disorder.

Does Charcot-Marie-Tooth get worse?

CMT is a progressive condition, which means the symptoms gradually get worse over time. This means it may be difficult to spot symptoms in young children who have CMT. Signs that a young child may have CMT include: appearing unusually clumsy and accident-prone for their age.

What is Charcot Charcot Marie Tooth disease?

Charcot-Marie-Tooth disease. Overview. Charcot (shahr-KOH)-Marie-Tooth disease is a group of inherited disorders that cause nerve damage. This damage is mostly in your arms and legs (peripheral nerves).

How does Charcot-Marie-Tooth disease affect the body?

As Charcot-Marie-Tooth disease progresses, symptoms may spread from the feet and legs to the hands and arms. The severity of symptoms can vary greatly from person to person, even among family members.

Does Charcot-Marie-Tooth (CMT) disease cause cardiac arrthymias?

Charcot-Marie-Tooth disease (peroneal muscular atrophy) has been reported to cause cardiac arrthymias and conduction disturbances in association with peripheral muscle atrophy.

What is the treatment for Charcot-Marie-Tooth disease?

Our case had a history of Charcot-Marie-Tooth disease. There is a high incidence of arrhythmia and embolic complications. The treatment usually consists of the medical management, defibrillator placement, and lifelong anticoagulation.