What are terminal inverted repeats?
Inverted terminal repeats that contain the origins of replication are present at the ends of the adenovirus genome. DNA synthesis is initiated at one of the two ends and proceeds to the other end.
What is the function of inverted repeat?
Inverted repeats have a number of important biological functions. They define the boundaries in transposons and indicate regions capable of self-complementary base pairing (regions within a single sequence which can base pair with each other).
Do retrotransposons have terminal inverted repeats?
Like LTR retrotransposons, non-LTR retrotransposons contain genes for reverse transcriptase, RNA-binding protein, nuclease, and sometimes ribonuclease H domain but they lack the long terminal repeats.
What are direct and inverted repeats?
Direct terminal repeats are in the same direction and inverted terminal repeats are opposite to each other in direction. Tandem repeats (tandem repeat sequences) are repeated copies which lie adjacent to each other. These can also be direct or inverted repeats.
What are SINEs and LINEs?
SINEs and LINEs are short and long interspersed retrotransposable elements, respectively, that invade new genomic sites using RNA intermediates. SINEs and LINEs are found in almost all eukaryotes (although not in Saccharomyces cerevisiae) and together account for at least 34% of the human genome.
How do transposons differ from retrotransposons?
How do transposons differ from retrotransposons? Transposons may or may not leave a copy behind at the original site, whereas retrotransposons always leave a copy behind at the original site. Transposons move by means of a DNA intermediate, whereas retrotransposons move by means of an RNA intermediate.
What is the difference between STRs and VNTRs?
VNTR and STR are two types of tandem repeats that form arrays of adjacent repetitive units in the eukaryotic genome. VNTR consists of comparatively a long repeating units of nucleotides (10-60 base pairs). STR consists of short repeating units of nucleotides (2-6 bp).
What are the two types of tandem repeats?
Tandem repeats (TR) are classified based on the length of the repeated motifs and consist of microsatellite DNA (short tandem repeats), minisatellite DNA, variable number of tandem repeats (VNTRs) and simple sequence repeats.
What are direct terminal repeats?
Flanking (or terminal) repeats (terminal repeat sequences) are sequences that are repeated on both ends of a sequence, for example, the long terminal repeats (LTRs) on retroviruses. Direct terminal repeats are in the same direction and inverted terminal repeats are opposite to each other in direction.