What diseases are caused by Spirochaetes?

Of mammalian pathogens, some of the most invasive come from a group of bacteria known as the spirochetes, which cause diseases such as syphilis, Lyme disease, relapsing fever and leptospirosis.

What are the three major spirochetes?

Spirochaetes are thin-walled spiralled flexible organisms which are motile by means of an axial filament….The three groups of spirochaetes include:

  • 1 Treponema.
  • 2 Leptospira.
  • 3 Borrelia.

What is the most common disease that damages the liver?

Viral infections: Hepatitis A, hepatitis B and hepatitis C are diseases caused by a viral infection. Problems with your immune system: When your immune system mistakenly attacks your liver, it can cause autoimmune liver diseases. These include primary biliary cholangitis and autoimmune hepatitis.

Can spirochetes be cured?

Late stage and early stages, as well as contacts of patients are treated with the same regimen. Those who are penicillin-allergic are treated with tetracycline or doxycycline for 14 days if greater than 8 years old, or erythromycin if less than 8 years old. Most patients get cured.

How do you get spirochetes?

Spirochetes of the genus Leptospira. These are typically acquired from animal contact, or water or soil contaminated by the urine of dogs, rats, or livestock in the course of recreation or work. Animals may remain asymptomatic shedders for years, and the organisms can remain viable after shedding for weeks to months.

Are spirochetes parasites?

The spirochete Borrelia burgdorferi is a tick-borne obligate parasite whose normal reservoir is a variety of small mammals [1]. Whereas infection of these natural hosts does not lead to disease, infection of humans can result in Lyme disease, as a consequence of the human immunopathological response to B.

How do you test for spirochetes?

Direct diagnosis. Just like other spirochetes of medical interest, Borrelia spp. responsible for Lyme borreliosis cannot be detected by standard optical microscopy or by Gram staining. They can, however, be detected by dark-field microscopy or phase-contrast microscopy [2].

Is spirochaetes a zoonotic disease?

Spirochaetes Summary Spirochaetes are gram-negative, anaerobic, motile bacteria WITHOUT an LPS. Zoonotic infections involve animal reservoirs of the bacteria with a zoonotic vector Lyme Disease is caused by Borrelia burgdoferi; spread by ticks; has both acute and chronic symptoms and is treated with doxycycline.

What is the pathophysiology of spirochetes?

Spirochetes are spiral-shaped bacteria that do not stain well by Gram stain or grow on culture media. There are three main pathogenic species: Treponema pallidum, which causes syphilis; Borrelia burgdorferi, which causes Lyme disease; and Leptospira interrogans, which causes leptospirosis.

What is the spirochete that causes Lyme disease?

Borrelia burgdorferi is the spirochete that causes Lyme disease. In contrast to T. pallidum, Borrelia has a unique nucleus containing a linear chromosome and linear plasmids. Borrelia is transmitted by tick bites ( Ixodes) during blood feeding.

What are Spirochaetes and what do they do?

Spirochaetes are a very unique group of bacteria but are responsible for a number of diseases, including dental conditions! This section will look at the basics of the bacteria as well as some examples of diseases. Gram-negative, however… No LPS!