What is the common site of giant cell tumor in long bones?

A giant cell tumor of bone is a type of benign (noncancerous) tumor that has a wide range of behaviors. These tumors typically grow at the ends of the body’s long bones. Most often, they appear at the lower end of the femur (thighbone) or upper end of the tibia (shinbone), close to the knee joint.

What is the prognosis of giant cell tumor?

A review of the world literature1,2,6,7,39,40 revealed an 80% to 85% survival rate in patients with pulmonary metastases from giant cell tumor of the bone. In fact, spontaneous regression of pulmonary lesions has been reported in the literature.

What percentage of giant cell tumor of bone are malignant?

We identified 4 large series of patients with malignant giant cell tumor of bone that provided data on 2315 patients with giant cell tumor of bone. Across these studies, the cumulative incidence of malignancy was 4.0%; the cumulative incidence of primary malignancy was 1.6% compared with 2.4% for secondary malignancy.

How fast does a giant cell tumor grow?

Giant cell tumor of bone (GCTB) in skeletally immature patients is rare, and little is known regarding how fast GCTB can grow. We report a case of a 10-year-old skeletally immature girl with pathologically proven GCTB with obvious growth plate invasion that showed surprisingly rapid growth over only 14 days.

How fast does giant cell tumor grow?

How often do giant cell tumors come back?

The local recurrence rate was 4.35% (1/23 cases) in patients treated through tumor resection and prosthesis replacement. Conversely, the local recurrence rate was higher in patients treated through tumor curettage and blurring, with a 24.56% incidence.

How do you get rid of a giant cell tumor?

How is a giant cell tumor treated?

  1. Surgery to remove the tumor and any damaged bone.
  2. Bone grafting.
  3. Bone reconstruction.
  4. Physical therapy to regain strength and mobility.
  5. Amputation, in severe cases.

How fast do giant cell tumors grow?

Can giant cell tumor be cured?

The goal for treatment of a giant cell tumor is to remove the tumor and prevent damage to the affected bone. Tumors that can’t be removed surgically can often be controlled and sometimes destroyed with radiation therapy. Giant cell tumors can come back.

Can giant cell tumors be malignant?

The term malignant giant cell tumor has been used in soft tissues to describe a tumor with a mixture of benign giant cells and malignant mononuclear cells. This has been considered to be a type of malignant fibrous histiocytoma and probably not related to true benign giant cell tumors of soft tissue.