What is the function of red pulp?

The red pulp of the spleen is composed of connective tissue known also as the cords of Billroth and many splenic sinusoids that are engorged with blood, giving it a red color. Its primary function is to filter the blood of antigens, microorganisms, and defective or worn-out red blood cells.

What are stave cells?

the endothelial cells being represented by. wooden staves, hence known as Stave cells. • Externally, the sinuses are encircled by reticular fibres in a transverse direction like the steel bands holding together the staves of the wooden barrel.

What is the splenic capsule?

The capsule of the spleen consists of dense irregular fibroelastic tissue. The connective tissue of the capsule contains contractile cells called myofibroblasts. By producing weak contraction of the capsule, these cells help to discharge the blood stored within the spleen into the circulation.

What is the difference between white pulp and red pulp?

The spleen contains two main types of tissue – white pulp and red pulp. White pulp is material which is part of the immune system (lymphatic tissue) mainly made up of white blood cells. Red pulp is made up of blood-filled cavities (venous sinuses) and splenic cords.

Where are stave cells found?

The endothelial stave cells that line venous sinuses in red pulp are long cells oriented lengthwise along the sinuses.

What is the Periarterial lymphatic sheath?

Periarteriolar lymphoid sheaths (or periarterial lymphatic sheaths, or PALS) are a portion of the white pulp of the spleen. They are populated largely by T cells and surround central arteries within the spleen; the PALS T-cells are presented with blood borne antigens via myeloid dendritic cells.

Can you live without a spleen?

Life without a spleen You can be active without a spleen, but you’re at increased risk of becoming sick or getting serious infections. This risk is highest shortly after surgery. People without a spleen may also have a harder time recovering from an illness or injury.

What is included in the GALT?

Gut-associated lymphoid tissue (GALT) includes Peyer’s patches, the appendix, and scattered solitary or isolated lymphoid follicles (ILFs). Peyer’s patches occur mainly in the ileum (less frequently in the jejunum) and consist of at least five aggregated lymphoid follicles (Fig.