What is the main mechanism by which vitamin B12 is absorbed?
Normally, vitamin B12 is readily absorbed in the last part of the small intestine (ileum), which leads to the large intestine. However, to be absorbed, the vitamin must combine with intrinsic factor, a protein produced in the stomach.
What is the mechanism of action of vitamin B complex?
As the building blocks of a healthy body, B vitamins have a direct impact on your energy levels, brain function, and cell metabolism. Vitamin B complex may help prevent infections and help support or promote: cell health. growth of red blood cells.
How does vitamin B12 function in the body?
Vitamin B12 is needed to form red blood cells and DNA. It is also a key player in the function and development of brain and nerve cells. Vitamin B12 binds to the protein in the foods we eat. In the stomach, hydrochloric acid and enzymes unbind vitamin B12 into its free form.
What is the reaction of vitamin B12?
Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing.
Which of the following steps of vitamin B12 absorption occurs in the stomach?
If the vitamin B12 is ingested in its protein bound form, it must first undergo a proteolytic cleavage in the stomach or duodenum where it will bind to an R-binder and enter into the duodenum for further cleavage.
What happens when vitamin B12 is deficient?
Constipation, diarrhea, loss of appetite, or gas. Nerve problems like numbness or tingling, muscle weakness, and problems walking. Vision loss. Mental problems like depression, memory loss, or behavioral changes.
What biochemical reactions are dependent on vitamin B12?
Of the many biochemical reactions in volving B12, only two are believed to occur in man: the isomerisation of L-methyl- malonyl-CoA to succinyl-CoA (not affected by folate; disturbance of this enzyme action is postulated as the cause of the degenera tive disease of the nervous system due to B12 deficiency), and the …
What protein is needed for vitamin B12 absorption in the intestine?