Why neonates are not given diazepam?
Diazepam is generally avoided in neonates because of its short duration of antiepileptic effect but very prolonged sedative effect, narrow therapeutic index, and the presence of sodium benzoate as a preservative.
What drug is given in a sedated newly delivered newborn?
When a stronger sedative effect is needed, one in three newborn infants is given midazolam (mostly in association with opioids), despite the lack of clinical evidence to support its use in this setting [24, 25].
Can midazolam be given to children?
In children aged 6 months to 12 years, midazolam is given as 0.05-0.1 mg/kg IV, titrated to the desired effect. Younger children (ie, < 5 years) may require larger cumulative doses, as high as 0.6 mg/kg or 6 mg.
How do you control a seizure in a neonate?
Current therapeutic options to treat neonatal seizures (i.e. primarily first-generation antiepileptic drugs [AEDs]) are relatively ineffective. In practice, phenobarbital still remains the drug of first choice for EEG confirmed or suspected seizures. Benzodiazepines are also used in (phenobarbital) refractory cases.
Which side effect is most common for midazolam?
drowsiness, hiccups, “oversedation,” or. injection site reactions (pain, swelling, redness, stiffness, blood clots, and tenderness).
Are NICU babies sedated?
In the NICU, children are often exposed to combinations of different analgesics and sedatives either simultaneously or sequentially, to reduce potential side effects.
What happens if you take versed while pregnant?
Versed can cause birth defects in an unborn baby, and generally should not be used during pregnancy. Tell your doctor if you are pregnant. Midazolam can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How should I take Versed?
Can you give versed to a newborn baby?
Midazolam injection should not be administered by rapid injection in the neonatal population as severe hypotension and seizures have been reported. Along with its needed effects, midazolam (the active ingredient contained in Versed) may cause some unwanted effects.
What are the side effects of versed for the elderly?
Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Versed. Common side effects may include: amnesia or forgetfulness after your procedure; drowsiness, dizziness; nausea, vomiting; runny nose, sneezing; or. blurred vision.
Is it safe to take other medications with versed?
Shortly after you are treated with Versed, using other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Sometimes it is not safe to use certain medications at the same time.